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Identification of an overprinting gene in Merkel cell polyomavirus provides evolutionary insight int...

Identification of an overprinting gene in Merkel cell polyomavirus provides evolutionary insight int...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1416696006

Identification of an overprinting gene in Merkel cell polyomavirus provides evolutionary insight into the birth of viral genes

About this item

Full title

Identification of an overprinting gene in Merkel cell polyomavirus provides evolutionary insight into the birth of viral genes

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (31), p.12744-12749

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Many viruses use overprinting (alternate reading frame utilization) as a means to increase protein diversity in genomes severely constrained by size. However, the evolutionary steps that facilitate the de novo generation of a novel protein within an ancestral ORF have remained poorly characterized. Here, we describe the identification of an overpri...

Alternative Titles

Full title

Identification of an overprinting gene in Merkel cell polyomavirus provides evolutionary insight into the birth of viral genes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1416696006

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1416696006

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1303526110

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