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Cabozantinib (XL184) for the treatment of locally advanced or metastatic progressive medullary thyro...

Cabozantinib (XL184) for the treatment of locally advanced or metastatic progressive medullary thyro...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1417532832

Cabozantinib (XL184) for the treatment of locally advanced or metastatic progressive medullary thyroid cancer

About this item

Full title

Cabozantinib (XL184) for the treatment of locally advanced or metastatic progressive medullary thyroid cancer

Publisher

England: Future Medicine Ltd

Journal title

Future oncology (London, England), 2013-08, Vol.9 (8), p.1083-1092

Language

English

Formats

Publication information

Publisher

England: Future Medicine Ltd

More information

Scope and Contents

Contents

Cabozantinib (XL184) is an oral multiple receptor tyrosine kinase inhibitor manufactured by Exelixis Inc., CA, USA. It mainly inhibits three tyrosine kinase receptors: MET, VEGFR2 and RET. In both preclinical and clinical studies it has been shown to inhibit tumor angiogenesis, invasiveness and metastases. The most frequent side effects are fatigue...

Alternative Titles

Full title

Cabozantinib (XL184) for the treatment of locally advanced or metastatic progressive medullary thyroid cancer

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1417532832

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1417532832

Other Identifiers

ISSN

1479-6694

E-ISSN

1744-8301

DOI

10.2217/fon.13.128

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