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Transforming growth factor-beta1 induces microvascular abnormalities through a down-modulation of ne...

Transforming growth factor-beta1 induces microvascular abnormalities through a down-modulation of ne...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1419359002

Transforming growth factor-beta1 induces microvascular abnormalities through a down-modulation of neural cell adhesion molecule in human hepatocellular carcinoma

About this item

Full title

Transforming growth factor-beta1 induces microvascular abnormalities through a down-modulation of neural cell adhesion molecule in human hepatocellular carcinoma

Publisher

New York: Elsevier Inc

Journal title

Laboratory investigation, 2012-09, Vol.92 (9), p.1297-1309

Language

English

Formats

Publication information

Publisher

New York: Elsevier Inc

More information

Scope and Contents

Contents

Hepatocellular carcinoma (HCC) is a very angiogenic and malignant cancer. Conventional chemotherapy is poorly effective because of the abnormal structural organization of HCC-infiltrating vessels. In previous work, we demonstrated that HCC angiogenesis is driven by transforming growth factor beta-1(TGF-β1)/CD105 axis, stimulating liver-derived micr...

Alternative Titles

Full title

Transforming growth factor-beta1 induces microvascular abnormalities through a down-modulation of neural cell adhesion molecule in human hepatocellular carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1419359002

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1419359002

Other Identifiers

ISSN

0023-6837

E-ISSN

1530-0307

DOI

10.1038/labinvest.2012.94

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