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CYP3A422 and CYP3A Combined Genotypes Both Correlate With Tacrolimus Disposition in Pediatric Heart...

CYP3A422 and CYP3A Combined Genotypes Both Correlate With Tacrolimus Disposition in Pediatric Heart...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1419362649

CYP3A422 and CYP3A Combined Genotypes Both Correlate With Tacrolimus Disposition in Pediatric Heart Transplant Recipients

About this item

Full title

CYP3A422 and CYP3A Combined Genotypes Both Correlate With Tacrolimus Disposition in Pediatric Heart Transplant Recipients

Publisher

England: Future Medicine Ltd

Journal title

Pharmacogenomics, 2013-07, Vol.14 (9), p.1027-1036

Language

English

Formats

Publication information

Publisher

England: Future Medicine Ltd

More information

Scope and Contents

Contents

Tacrolimus metabolism depends on CYP3A4 and CYP3A5. We aimed to determine the relationship between the CYP3A4*22 polymorphism and combined CYP3A genotypes with tacrolimus disposition in pediatric heart transplant recipients.
Sixty pediatric heart transplant recipients were included. Tacrolimus doses and trough concentrations were collected in th...

Alternative Titles

Full title

CYP3A422 and CYP3A Combined Genotypes Both Correlate With Tacrolimus Disposition in Pediatric Heart Transplant Recipients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1419362649

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1419362649

Other Identifiers

ISSN

1462-2416

E-ISSN

1744-8042

DOI

10.2217/pgs.13.80

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