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Influence of UDP-glucuronosyltransferase polymorphisms on valproic acid pharmacokinetics in Chinese...

Influence of UDP-glucuronosyltransferase polymorphisms on valproic acid pharmacokinetics in Chinese...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1419367245

Influence of UDP-glucuronosyltransferase polymorphisms on valproic acid pharmacokinetics in Chinese epilepsy patients

About this item

Full title

Influence of UDP-glucuronosyltransferase polymorphisms on valproic acid pharmacokinetics in Chinese epilepsy patients

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

European journal of clinical pharmacology, 2012-10, Vol.68 (10), p.1395-1401

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

Purpose
The aim of this study was to investigate the genetic polymorphisms of UGT1A3, UGT1A6, and UGT2B7 in Chinese epilepsy patients and their potential influence on the pharmacokinetics of valproic acid (VPA).
Methods
The genetic architectures of UGT1A3, UGT1A6, and UGT2B7 in 242 epilepsy patients were detected by DNA sequencing and PCR-...

Alternative Titles

Full title

Influence of UDP-glucuronosyltransferase polymorphisms on valproic acid pharmacokinetics in Chinese epilepsy patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1419367245

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1419367245

Other Identifiers

ISSN

0031-6970

E-ISSN

1432-1041

DOI

10.1007/s00228-012-1277-7

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