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TREM2 in Alzheimer’s disease

TREM2 in Alzheimer’s disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1419371731

TREM2 in Alzheimer’s disease

About this item

Full title

TREM2 in Alzheimer’s disease

Publisher

Boston: Springer US

Journal title

Molecular neurobiology, 2013-08, Vol.48 (1), p.180-185

Language

English

Formats

Publication information

Publisher

Boston: Springer US

More information

Scope and Contents

Contents

Recent works have demonstrated a rare functional variant (R47H) in triggering receptor expressed on myeloid cells (TREM) 2 gene, encoding TREM2 protein, increase susceptibility to late-onset Alzheimer’s disease (AD), with an odds ratio similar to that of the apolipoprotein E ε4 allele. The reduced function of TREM2 was speculated to be the main cau...

Alternative Titles

Full title

TREM2 in Alzheimer’s disease

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1419371731

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1419371731

Other Identifiers

ISSN

0893-7648

E-ISSN

1559-1182

DOI

10.1007/s12035-013-8424-8

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