MYD88 L265P is a marker highly characteristic of, but not restricted to, Waldenström’s macroglobulin...
MYD88 L265P is a marker highly characteristic of, but not restricted to, Waldenström’s macroglobulinemia
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Author / Creator
Jiménez, C , Sebastián, E , Chillón, M C , Giraldo, P , Mariano Hernández, J , Escalante, F , González-López, T J , Aguilera, C , de Coca, A G , Murillo, I , Alcoceba, M , Balanzategui, A , Sarasquete, M E , Corral, R , Marín, L A , Paiva, B , Ocio, E M , Gutiérrez, N C , González, M , San Miguel, J F and García-Sanz, R
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
We evaluated the MYD88 L265P mutation in Waldenström’s macroglobulinemia (WM) and B-cell lymphoproliferative disorders by specific polymerase chain reaction (PCR) (sensitivity ∼10
−3
). No mutation was seen in normal donors, while it was present in 101/117 (86%) WM patients, 27/31 (87%) IgM monoclonal gammapathies of uncertain significance (M...
Alternative Titles
Full title
MYD88 L265P is a marker highly characteristic of, but not restricted to, Waldenström’s macroglobulinemia
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Record Identifier
TN_cdi_proquest_miscellaneous_1427004936
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1427004936
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ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/leu.2013.62
