Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's d...
Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models
About this item
Full title
Author / Creator
Marco, Sonia , Giralt, Albert , Petrovic, Milos M , Pouladi, Mahmoud A , Martínez-Turrillas, Rebeca , Martínez-Hernández, José , Kaltenbach, Linda S , Torres-Peraza, Jesús , Graham, Rona K , Watanabe, Masahiko , Luján, Rafael , Nakanishi, Nobuki , Lipton, Stuart A , Lo, Donald C , Hayden, Michael R , Alberch, Jordi , Wesseling, John F and Pérez-Otaño, Isabel
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Huntington's disease is a neurodegenerative disorder associated with glutamate receptor dysfunction. Now Isabel Pérez-Otaño and colleagues report that the HTT protein that aggregates in the brains of individuals with the disease disrupts the ability of the adaptor protein PACSIN1 to keep the glutamate receptor subunit GluN3A away from the surface o...
Alternative Titles
Full title
Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models
Authors, Artists and Contributors
Author / Creator
Giralt, Albert
Petrovic, Milos M
Pouladi, Mahmoud A
Martínez-Turrillas, Rebeca
Martínez-Hernández, José
Kaltenbach, Linda S
Torres-Peraza, Jesús
Graham, Rona K
Watanabe, Masahiko
Luján, Rafael
Nakanishi, Nobuki
Lipton, Stuart A
Lo, Donald C
Hayden, Michael R
Alberch, Jordi
Wesseling, John F
Pérez-Otaño, Isabel
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1430857154
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1430857154
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.3246
