Bispecific antibodies with natural architecture produced by co-culture of bacteria expressing two di...
Bispecific antibodies with natural architecture produced by co-culture of bacteria expressing two distinct half-antibodies
About this item
Full title
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Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
In a bacterial expression system, two half antibodies, each having distinct light chains, spontaneously assemble into an intact bispecific molecule with natural antibody architecture
By enabling the simultaneous engagement of two distinct targets, bispecific antibodies broaden the potential utility of antibody-based therapies. However, bispecifi...
Alternative Titles
Full title
Bispecific antibodies with natural architecture produced by co-culture of bacteria expressing two distinct half-antibodies
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Record Identifier
TN_cdi_proquest_miscellaneous_1434014852
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1434014852
Other Identifiers
ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.2621
