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D-chiro-inositol Negatively Regulates the Formation of Multinucleated Osteoclasts by Down-Regulating...

D-chiro-inositol Negatively Regulates the Formation of Multinucleated Osteoclasts by Down-Regulating...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1434017195

D-chiro-inositol Negatively Regulates the Formation of Multinucleated Osteoclasts by Down-Regulating NFATc1

About this item

Full title

D-chiro-inositol Negatively Regulates the Formation of Multinucleated Osteoclasts by Down-Regulating NFATc1

Publisher

Boston: Springer US

Journal title

Journal of clinical immunology, 2012-12, Vol.32 (6), p.1360-1371

Language

English

Formats

Publication information

Publisher

Boston: Springer US

More information

Scope and Contents

Contents

Purpose
Osteoclasts (OCs) are multinucleated giant cells that resorb bone matrix. Accelerated bone destruction by OCs might cause several metabolic bone-related diseases, such as osteoporosis and inflammatory bone loss. D-pinitol (3-
O
-methyl-D-chiro-inositol) is a prominent component of dietary legumes and is actively converted to D-chir...

Alternative Titles

Full title

D-chiro-inositol Negatively Regulates the Formation of Multinucleated Osteoclasts by Down-Regulating NFATc1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1434017195

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1434017195

Other Identifiers

ISSN

0271-9142

E-ISSN

1573-2592

DOI

10.1007/s10875-012-9722-z

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