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Gene Therapy Model of X-linked Severe Combined Immunodeficiency Using a Modified Foamy Virus Vector....

Gene Therapy Model of X-linked Severe Combined Immunodeficiency Using a Modified Foamy Virus Vector....

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1439217941

Gene Therapy Model of X-linked Severe Combined Immunodeficiency Using a Modified Foamy Virus Vector. e71594

About this item

Full title

Gene Therapy Model of X-linked Severe Combined Immunodeficiency Using a Modified Foamy Virus Vector. e71594

Journal title

PloS one, 2013-08, Vol.8 (8)

Language

English

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Subjects

Subjects and topics

More information

Scope and Contents

Contents

X-linked severe combined immunodeficiency (SCID-X1) is an inherited genetic immunodeficiency associated with mutations in the common cytokine receptor gamma chain ( gamma c) gene, and characterized by a complete defect of T and natural killer (NK) cells. Gene therapy for SCID-X1 using conventional retroviral (RV) vectors carrying the gamma c gene r...

Alternative Titles

Full title

Gene Therapy Model of X-linked Severe Combined Immunodeficiency Using a Modified Foamy Virus Vector. e71594

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Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1439217941

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1439217941

Other Identifiers

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0071594

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