Comparative Anatomy of Chromosomal Domains with Imprinted and Non-Imprinted Allele-Specific DNA Meth...
Comparative Anatomy of Chromosomal Domains with Imprinted and Non-Imprinted Allele-Specific DNA Methylation: e1003622
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Author / Creator
Paliwal, Anupam , Temkin, Alexis M , Kerkel, Kristi , Yale, Alexander , Yotova, Iveta , Drost, Natalia , Lax, Simon , Nhan-Chang, Chia-Ling , Powell, Charles , Borczuk, Alain , Aviv, Abraham , Wapner, Ronald , Chen, Xiaowei , Nagy, Peter L , Schork, Nicholas , Do, Catherine , Torkamani, Ali and Tycko, Benjamin
Publisher
San Francisco: Public Library of Science
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Language
English
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Publisher
San Francisco: Public Library of Science
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Contents
Allele-specific DNA methylation (ASM) is well studied in imprinted domains, but this type of epigenetic asymmetry is actually found more commonly at non-imprinted loci, where the ASM is dictated not by parent-of-origin but instead by the local haplotype. We identified loci with strong ASM in human tissues from methylation-sensitive SNP array data....
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Full title
Comparative Anatomy of Chromosomal Domains with Imprinted and Non-Imprinted Allele-Specific DNA Methylation: e1003622
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TN_cdi_proquest_miscellaneous_1439233487
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1439233487
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ISSN
1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1003622
