T cell regulation mediated by interaction of soluble CD52 with the inhibitory receptor Siglec-10
T cell regulation mediated by interaction of soluble CD52 with the inhibitory receptor Siglec-10
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
CD52 is an important target for depleting antibodies; however, its physiological ligand and function have been unclear. Harrison and colleagues show that soluble CD52 is used by certain CD4
+
cells to suppress target cells via the inhibitory receptor Siglec-10.
Functionally diverse T cell populations interact to maintain homeostasis of the...
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Full title
T cell regulation mediated by interaction of soluble CD52 with the inhibitory receptor Siglec-10
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TN_cdi_proquest_miscellaneous_1443367135
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1443367135
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.2610
