Deterministic direct reprogramming of somatic cells to pluripotency
Deterministic direct reprogramming of somatic cells to pluripotency
About this item
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Author / Creator
Rais, Yoach , Zviran, Asaf , Geula, Shay , Gafni, Ohad , Chomsky, Elad , Viukov, Sergey , Mansour, Abed AlFatah , Caspi, Inbal , Krupalnik, Vladislav , Zerbib, Mirie , Maza, Itay , Mor, Nofar , Baran, Dror , Weinberger, Leehee , Jaitin, Diego A. , Lara-Astiaso, David , Blecher-Gonen, Ronnie , Shipony, Zohar , Mukamel, Zohar , Hagai, Tzachi , Gilad, Shlomit , Amann-Zalcenstein, Daniela , Tanay, Amos , Amit, Ido , Novershtern, Noa and Hanna, Jacob H.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Somatic cells can be inefficiently and stochastically reprogrammed into induced pluripotent stem (iPS) cells by exogenous expression of Oct4 (also called Pou5f1), Sox2, Klf4 and Myc (hereafter referred to as OSKM). The nature of the predominant rate-limiting barrier(s) preventing the majority of cells to successfully and synchronously reprogram rem...
Alternative Titles
Full title
Deterministic direct reprogramming of somatic cells to pluripotency
Authors, Artists and Contributors
Author / Creator
Zviran, Asaf
Geula, Shay
Gafni, Ohad
Chomsky, Elad
Viukov, Sergey
Mansour, Abed AlFatah
Caspi, Inbal
Krupalnik, Vladislav
Zerbib, Mirie
Maza, Itay
Mor, Nofar
Baran, Dror
Weinberger, Leehee
Jaitin, Diego A.
Lara-Astiaso, David
Blecher-Gonen, Ronnie
Shipony, Zohar
Mukamel, Zohar
Hagai, Tzachi
Gilad, Shlomit
Amann-Zalcenstein, Daniela
Tanay, Amos
Amit, Ido
Novershtern, Noa
Hanna, Jacob H.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1443385334
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1443385334
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature12587