Log in to save to my catalogue

Deterministic direct reprogramming of somatic cells to pluripotency

Deterministic direct reprogramming of somatic cells to pluripotency

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1443385334

Deterministic direct reprogramming of somatic cells to pluripotency

About this item

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Somatic cells can be inefficiently and stochastically reprogrammed into induced pluripotent stem (iPS) cells by exogenous expression of Oct4 (also called Pou5f1), Sox2, Klf4 and Myc (hereafter referred to as OSKM). The nature of the predominant rate-limiting barrier(s) preventing the majority of cells to successfully and synchronously reprogram rem...

Alternative Titles

Full title

Deterministic direct reprogramming of somatic cells to pluripotency

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1443385334

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1443385334

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature12587

How to access this item