The BH3 mimetic S1 induces endoplasmic reticulum stress-associated apoptosis in cisplatin-resistant...
The BH3 mimetic S1 induces endoplasmic reticulum stress-associated apoptosis in cisplatin-resistant human ovarian cancer cells although it activates autophagy
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Author / Creator
LIU, NING , XU, YE , SUN, JI-TONG , SU, JING , XIANG, XI-YAN , YI, HAO-WEI , ZHANG, ZHI-CHAO and SUN, LIAN-KUN
Publisher
Greece: D.A. Spandidos
Journal title
Language
English
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Publication information
Publisher
Greece: D.A. Spandidos
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Scope and Contents
Contents
SKOV3/DDP human ovarian cancer cells have been shown to be resistant to cisplatin. Although the BH3 mimetic S1 induces cell death in several types of tumor cells, it is unclear whether it induces death in drug-resistant cells. Herein, we found that S1 induced endoplasmic reticulum (ER) stress-associated apoptosis in both SKOV3 and SKOV3/DDP cells....
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Full title
The BH3 mimetic S1 induces endoplasmic reticulum stress-associated apoptosis in cisplatin-resistant human ovarian cancer cells although it activates autophagy
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Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_1443994102
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1443994102
Other Identifiers
ISSN
1021-335X
E-ISSN
1791-2431
DOI
10.3892/or.2013.2771
