Using synthetic templates to design an unbiased multiplex PCR assay
Using synthetic templates to design an unbiased multiplex PCR assay
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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T and B cell receptor loci undergo combinatorial rearrangement, generating a diverse immune receptor repertoire, which is vital for recognition of potential antigens. Here we use a multiplex PCR with a mixture of primers targeting the rearranged variable and joining segments to capture receptor diversity. Differential hybridization kinetics can int...
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Full title
Using synthetic templates to design an unbiased multiplex PCR assay
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TN_cdi_proquest_miscellaneous_1445913485
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1445913485
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms3680
