Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs
Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs
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Author / Creator
Gulbins, Erich , Palmada, Monica , Reichel, Martin , Lüth, Anja , Böhmer, Christoph , Amato, Davide , Müller, Christian P , Tischbirek, Carsten H , Groemer, Teja W , Tabatabai, Ghazaleh , Becker, Katrin A , Tripal, Philipp , Staedtler, Sven , Ackermann, Teresa F , van Brederode, Johannes , Alzheimer, Christian , Weller, Michael , Lang, Undine E , Kleuser, Burkhard , Grassmé, Heike and Kornhuber, Johannes
Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Depression is a debilitating condition for which new treatments are sorely needed. Now, Erich Gulbins and his colleagues report that reducing ceramide levels in the brain has antidepressant effects in mouse models of the disease.
Major depression is a highly prevalent severe mood disorder that is treated with antidepressants. The molecular targe...
Alternative Titles
Full title
Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs
Authors, Artists and Contributors
Author / Creator
Palmada, Monica
Reichel, Martin
Lüth, Anja
Böhmer, Christoph
Amato, Davide
Müller, Christian P
Tischbirek, Carsten H
Groemer, Teja W
Tabatabai, Ghazaleh
Becker, Katrin A
Tripal, Philipp
Staedtler, Sven
Ackermann, Teresa F
van Brederode, Johannes
Alzheimer, Christian
Weller, Michael
Lang, Undine E
Kleuser, Burkhard
Grassmé, Heike
Kornhuber, Johannes
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1448215634
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1448215634
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.3214