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Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs

Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1448215634

Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs

About this item

Full title

Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2013-07, Vol.19 (7), p.934-938

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Depression is a debilitating condition for which new treatments are sorely needed. Now, Erich Gulbins and his colleagues report that reducing ceramide levels in the brain has antidepressant effects in mouse models of the disease.
Major depression is a highly prevalent severe mood disorder that is treated with antidepressants. The molecular targe...

Alternative Titles

Full title

Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1448215634

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1448215634

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm.3214

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