Manipulating L-type calcium channels in cardiomyocytes using split-intein protein transsplicing
Manipulating L-type calcium channels in cardiomyocytes using split-intein protein transsplicing
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Manipulating expression of large genes (>6 kb) in adult cardiomyocytes is challenging because these cells are only efficiently transduced by viral vectors with a 4–7 kb packaging capacity. This limitation impedes understanding structure–function mechanisms of important proteins in heart. L-type calcium channels (LTCCs) regulate diverse facets of ca...
Alternative Titles
Full title
Manipulating L-type calcium channels in cardiomyocytes using split-intein protein transsplicing
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Record Identifier
TN_cdi_proquest_miscellaneous_1458530052
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1458530052
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1308161110
