Loss of glucocorticoid receptor activation is a hallmark of BRCA1-mutated breast tissue
Loss of glucocorticoid receptor activation is a hallmark of BRCA1-mutated breast tissue
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Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Scope and Contents
Contents
Glucocorticoids (GCs) regulate cell homeostasis and can affect carcinogenesis. An inherited germline mutation in the BRCA1 gene, a tumor suppressor gene, confers a predisposition to breast and ovarian cancers. BRCA1 participates in the maintenance of genome stability through DNA repair, in cellular homeostasis through gene transcription, and in sig...
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Full title
Loss of glucocorticoid receptor activation is a hallmark of BRCA1-mutated breast tissue
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TN_cdi_proquest_miscellaneous_1459974823
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1459974823
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ISSN
0167-6806,1573-7217
E-ISSN
1573-7217
DOI
10.1007/s10549-013-2722-8
