Novel anti-Plasmodial hits identified by virtual screening of the ZINC database
Novel anti-Plasmodial hits identified by virtual screening of the ZINC database
About this item
Full title
Author / Creator
Publisher
Dordrecht: Springer Netherlands
Journal title
Language
English
Formats
Publication information
Publisher
Dordrecht: Springer Netherlands
Subjects
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Scope and Contents
Contents
Increased resistance of
Plasmodium falciparum
to most available drugs challenges the control of malaria. Studies with protease inhibitors have suggested important roles for the falcipain family of cysteine proteases. These enzymes act in concert with other proteases to hydrolyze host erythrocyte hemoglobin in the parasite food vacuole. In ord...
Alternative Titles
Full title
Novel anti-Plasmodial hits identified by virtual screening of the ZINC database
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1461338432
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1461338432
Other Identifiers
ISSN
0920-654X
E-ISSN
1573-4951
DOI
10.1007/s10822-013-9685-z
