IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication
IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Replication of lentiviruses generates different DNA forms, including RNA:DNA hybrids, ssDNA, and dsDNA. Nucleic acids stimulate innate immune responses, and pattern recognition receptors detecting dsDNA have been identified. However, sensors for ssDNA have not been reported, and the ability of RNA:DNA hybrids to stimulate innate immune responses is...
Alternative Titles
Full title
IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication
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Record Identifier
TN_cdi_proquest_miscellaneous_1462371957
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1462371957
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1311669110
