A functional autophagy pathway is required for rapamycin-induced degradation of the Sgs1 helicase in...
A functional autophagy pathway is required for rapamycin-induced degradation of the Sgs1 helicase in Saccharomyces cerevisiae
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Canada: NRC Research Press
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Language
English
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Publisher
Canada: NRC Research Press
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In yeast Saccharomyces cerevisiae, the immunosuppressant rapamycin mimics starvation by inhibiting the kinase Tor1. We recently documented that this treatment triggers a rapid degradation of Sgs1, a helicase involved in several biological processes such as the prevention of genomic instability. Herein, we show that yeast strains deleted for genes A...
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A functional autophagy pathway is required for rapamycin-induced degradation of the Sgs1 helicase in Saccharomyces cerevisiae
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TN_cdi_proquest_miscellaneous_1464511221
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1464511221
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ISSN
0829-8211
E-ISSN
1208-6002
DOI
10.1139/bcb-2012-0084
