A Mutation in the SUV39H2 Gene in Labrador Retrievers with Hereditary Nasal Parakeratosis (HNPK) Pro...
A Mutation in the SUV39H2 Gene in Labrador Retrievers with Hereditary Nasal Parakeratosis (HNPK) Provides Insights into the Epigenetics of Keratinocyte Differentiation: e1003848
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Author / Creator
Jagannathan, Vidhya , Bannoehr, Jeanette , Plattet, Philippe , Hauswirth, Regula , Drögemüller, Cord , Drögemüller, Michaela , Wiener, Dominique J , Doherr, Marcus , Owczarek-Lipska, Marta , Galichet, Arnaud , Welle, Monika M , Tengvall, Katarina , Bergvall, Kerstin , Lohi, Hannes , Rüfenacht, Silvia , Linek, Monika , Paradis, Manon , Müller, Eliane J , Roosje, Petra and Leeb, Tosso
Publisher
San Francisco: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
San Francisco: Public Library of Science
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Scope and Contents
Contents
Hereditary nasal parakeratosis (HNPK), an inherited monogenic autosomal recessive skin disorder, leads to crusts and fissures on the nasal planum of Labrador Retrievers. We performed a genome-wide association study (GWAS) using 13 HNPK cases and 23 controls. We obtained a single strong association signal on chromosome 2 (praw = 4.4×10-14). The anal...
Alternative Titles
Full title
A Mutation in the SUV39H2 Gene in Labrador Retrievers with Hereditary Nasal Parakeratosis (HNPK) Provides Insights into the Epigenetics of Keratinocyte Differentiation: e1003848
Authors, Artists and Contributors
Author / Creator
Bannoehr, Jeanette
Plattet, Philippe
Hauswirth, Regula
Drögemüller, Cord
Drögemüller, Michaela
Wiener, Dominique J
Doherr, Marcus
Owczarek-Lipska, Marta
Galichet, Arnaud
Welle, Monika M
Tengvall, Katarina
Bergvall, Kerstin
Lohi, Hannes
Rüfenacht, Silvia
Linek, Monika
Paradis, Manon
Müller, Eliane J
Roosje, Petra
Leeb, Tosso
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1464511902
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1464511902
Other Identifiers
ISSN
1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1003848
