Discrepancy between in vitro and in vivo antitumor effect of a new platinum(II) metallointercalator
Discrepancy between in vitro and in vivo antitumor effect of a new platinum(II) metallointercalator
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Publisher
Boston: Springer US
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Language
English
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Boston: Springer US
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Summary
Platinum(II) metallointercalators represent a new class of DNA-damaging antitumor complexes active in cisplatin- and oxaliplatin-resistant cell lines. In the first part of our work, we have screened in vitro a serie of 18 metallointercalators with the structure [Pt(A
L
)(I
L
)]
2+
where A
L
= ethylenediamine (EN)...
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Full title
Discrepancy between in vitro and in vivo antitumor effect of a new platinum(II) metallointercalator
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TN_cdi_proquest_miscellaneous_1468377114
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1468377114
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ISSN
0167-6997
E-ISSN
1573-0646
DOI
10.1007/s10637-010-9461-z
