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Therapeutic Concentrations of Mitoxantrone Elicit Energetic Imbalance in H9c2 Cells as an Earlier Ev...

Therapeutic Concentrations of Mitoxantrone Elicit Energetic Imbalance in H9c2 Cells as an Earlier Ev...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1468382406

Therapeutic Concentrations of Mitoxantrone Elicit Energetic Imbalance in H9c2 Cells as an Earlier Event

About this item

Full title

Therapeutic Concentrations of Mitoxantrone Elicit Energetic Imbalance in H9c2 Cells as an Earlier Event

Publisher

Boston: Springer US

Journal title

Cardiovascular toxicology, 2013-12, Vol.13 (4), p.413-425

Language

English

Formats

Publication information

Publisher

Boston: Springer US

More information

Scope and Contents

Contents

Mitoxantrone (MTX) is a chemotherapeutic agent that emerged as an alternative to anthracycline therapy. However, MTX also causes late cardiotoxicity, being oxidative stress and mitochondrial-impaired function proposed as possible mechanisms. This work aimed to investigate the relevance of these mechanisms to the MTX toxicity in H9c2 cells, using th...

Alternative Titles

Full title

Therapeutic Concentrations of Mitoxantrone Elicit Energetic Imbalance in H9c2 Cells as an Earlier Event

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1468382406

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1468382406

Other Identifiers

ISSN

1530-7905

E-ISSN

1559-0259

DOI

10.1007/s12012-013-9224-0

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