Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis
Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Regulatory T (T
reg
) cells exhibit substantial phenotypic and functional plasticity. Hiroshi Takayanagi and his colleagues report that in autoimmune arthritis, a subset of T
reg
cells can lose Foxp3 expression and convert into T
H
17 cells. This conversion is mediated by synovial fibroblast-derived IL-6, and
in vivo
, these...
Alternative Titles
Full title
Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1490728887
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1490728887
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.3432
