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Identification of the incednine biosynthetic gene cluster: characterization of novel β-glutamate-β-d...

Identification of the incednine biosynthetic gene cluster: characterization of novel β-glutamate-β-d...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1490779743

Identification of the incednine biosynthetic gene cluster: characterization of novel β-glutamate-β-decarboxylase IdnL3

About this item

Full title

Identification of the incednine biosynthetic gene cluster: characterization of novel β-glutamate-β-decarboxylase IdnL3

Publisher

London: Nature Publishing Group UK

Journal title

Journal of antibiotics, 2013-12, Vol.66 (12), p.691-699

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

A biosynthetic gene cluster for the 24-membered macrolactam antibiotic incednine was identified from the producer strain,
Streptomyces
sp. ML694-90F3. Among the putative incednine biosynthetic enzymes, a novel pyridoxal 5′-phosphate (PLP)-dependent β-glutamate-β-decarboxylase, IdnL3, was functionally characterized
in vitro
by demonstrat...

Alternative Titles

Full title

Identification of the incednine biosynthetic gene cluster: characterization of novel β-glutamate-β-decarboxylase IdnL3

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1490779743

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1490779743

Other Identifiers

ISSN

0021-8820

E-ISSN

1881-1469

DOI

10.1038/ja.2013.76

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