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Increased NLRP3-dependent interleukin 1β secretion in patients with familial Mediterranean fever: co...

Increased NLRP3-dependent interleukin 1β secretion in patients with familial Mediterranean fever: co...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1490785701

Increased NLRP3-dependent interleukin 1β secretion in patients with familial Mediterranean fever: correlation with MEFV genotype

About this item

Full title

Increased NLRP3-dependent interleukin 1β secretion in patients with familial Mediterranean fever: correlation with MEFV genotype

Publisher

England

Journal title

Annals of the rheumatic diseases, 2014-02, Vol.73 (2), p.462-469

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

Objectives To define in patients affected by familial Mediterranean fever (FMF) whether or not interleukin (IL)-1β secretion (1) is enhanced, (2) correlates with the type of MEFV mutation and (3) is mediated by NLRP3. Methods Freshly isolated monocytes from 21 patients with FMF (12 homozygous and 9 heterozygous), 14 MEFV healthy carriers and 30 hea...

Alternative Titles

Full title

Increased NLRP3-dependent interleukin 1β secretion in patients with familial Mediterranean fever: correlation with MEFV genotype

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1490785701

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1490785701

Other Identifiers

ISSN

0003-4967

E-ISSN

1468-2060

DOI

10.1136/annrheumdis-2012-202774

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