A dual role for autophagy in a murine model of lung cancer
A dual role for autophagy in a murine model of lung cancer
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Author / Creator
Rao, Shuan , Tortola, Luigi , Perlot, Thomas , Wirnsberger, Gerald , Novatchkova, Maria , Nitsch, Roberto , Sykacek, Peter , Frank, Lukas , Schramek, Daniel , Komnenovic, Vukoslav , Sigl, Verena , Aumayr, Karin , Schmauss, Gerald , Fellner, Nicole , Handschuh, Stephan , Glösmann, Martin , Pasierbek, Pawel , Schlederer, Michaela , Resch, Guenter P. , Ma, Yuting , Yang, Heng , Popper, Helmuth , Kenner, Lukas , Kroemer, Guido and Penninger, Josef M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Autophagy is a mechanism by which starving cells can control their energy requirements and metabolic states, thus facilitating the survival of cells in stressful environments, in particular in the pathogenesis of cancer. Here we report that tissue-specific inactivation of
Atg5
, essential for the formation of autophagosomes, markedly impairs...
Alternative Titles
Full title
A dual role for autophagy in a murine model of lung cancer
Authors, Artists and Contributors
Author / Creator
Tortola, Luigi
Perlot, Thomas
Wirnsberger, Gerald
Novatchkova, Maria
Nitsch, Roberto
Sykacek, Peter
Frank, Lukas
Schramek, Daniel
Komnenovic, Vukoslav
Sigl, Verena
Aumayr, Karin
Schmauss, Gerald
Fellner, Nicole
Handschuh, Stephan
Glösmann, Martin
Pasierbek, Pawel
Schlederer, Michaela
Resch, Guenter P.
Ma, Yuting
Yang, Heng
Popper, Helmuth
Kenner, Lukas
Kroemer, Guido
Penninger, Josef M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1491058369
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1491058369
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms4056
