Breast and ovarian cancer risks in a large series of clinically ascertained families with a high pro...
Breast and ovarian cancer risks in a large series of clinically ascertained families with a high proportion of BRCA1 and BRCA2 Dutch founder mutations
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Author / Creator
Brohet, Richard M , Velthuizen, Maria E , Hogervorst, Frans B L , EJ Meijers-Heijboer, Hanne , Seynaeve, Caroline , Collée, Margriet J , Verhoef, Senno , Ausems, Margreet G E M , Hoogerbrugge, Nicoline , van Asperen, Christi J , Gómez García, Encarna , Menko, Fred , Oosterwijk, Jan C , Devilee, Peter , Veer, Laura J van't , van Leeuwen, Flora E , Easton, Douglas F , Rookus, Matti A , Antoniou, Antonis C and HEBON Resource
Publisher
England: BMJ Publishing Group LTD
Journal title
Language
English
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Publisher
England: BMJ Publishing Group LTD
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Scope and Contents
Contents
Background BRCA1 or BRCA2 mutations confer increased risks of breast and ovarian cancer, but risks have been found to vary across studies and populations. Methods We ascertained pedigree data of 582 BRCA1 and 176 BRCA2 families and studied the variation in breast and ovarian cancer risks using a modified segregation analysis model. Results The aver...
Alternative Titles
Full title
Breast and ovarian cancer risks in a large series of clinically ascertained families with a high proportion of BRCA1 and BRCA2 Dutch founder mutations
Authors, Artists and Contributors
Author / Creator
Velthuizen, Maria E
Hogervorst, Frans B L
EJ Meijers-Heijboer, Hanne
Seynaeve, Caroline
Collée, Margriet J
Verhoef, Senno
Ausems, Margreet G E M
Hoogerbrugge, Nicoline
van Asperen, Christi J
Gómez García, Encarna
Menko, Fred
Oosterwijk, Jan C
Devilee, Peter
Veer, Laura J van't
van Leeuwen, Flora E
Easton, Douglas F
Rookus, Matti A
Antoniou, Antonis C
HEBON Resource
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1491062042
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1491062042
Other Identifiers
ISSN
0022-2593
E-ISSN
1468-6244
DOI
10.1136/jmedgenet-2013-101974
