Evidence of mitochondrial dysfunction and impaired ROS detoxifying machinery in Fanconi Anemia cells
Evidence of mitochondrial dysfunction and impaired ROS detoxifying machinery in Fanconi Anemia cells
About this item
Full title
Author / Creator
Kumari, U , Ya Jun, W , Huat Bay, B and Lyakhovich, A
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Fanconi Anemia (FA) is a rare genetic disorder associated with a bone-marrow failure, cancer predisposition and hypersensitivity to DNA crosslinking agents. Majority of the 15 FA genes and encoded proteins characterized so far are integrated into DNA repair pathways, however, other important functions cannot be excluded. FA cells are sensitive to o...
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Full title
Evidence of mitochondrial dysfunction and impaired ROS detoxifying machinery in Fanconi Anemia cells
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Record Identifier
TN_cdi_proquest_miscellaneous_1492633134
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1492633134
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ISSN
0950-9232,1476-5594
E-ISSN
1476-5594
DOI
10.1038/onc.2012.583
