Characterization of Two Distinct Lymphoproliferative Diseases Caused by Ectopic Expression of the No...
Characterization of Two Distinct Lymphoproliferative Diseases Caused by Ectopic Expression of the Notch Ligand DLL4 on T Cells: e84841
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English
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Notch signaling is essential for the development of T cell progenitors through the interaction of NOTCH1 receptor on their surface with the ligand, Delta-like 4 (DLL4), which is expressed by the thymic epithelial cells. Notch signaling is quickly shut down once the cells pass beta -selection, and CD4/CD8 double positive (DP) cells are unresponsive...
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Characterization of Two Distinct Lymphoproliferative Diseases Caused by Ectopic Expression of the Notch Ligand DLL4 on T Cells: e84841
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TN_cdi_proquest_miscellaneous_1492641455
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1492641455
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1932-6203
DOI
10.1371/journal.pone.0084841
