Generation of GGTA1 biallelic knockout pigs via zinc-finger nucleases and somatic cell nuclear trans...
Generation of GGTA1 biallelic knockout pigs via zinc-finger nucleases and somatic cell nuclear transfer
About this item
Full title
Author / Creator
Bao, Lei , Chen, HaiDe , Jong, UiMyong , Rim, CholHo , Li, WenLing , Lin, XiJuan , Zhang, Dan , Luo, Qiong , Cui, Chun , Huang, HeFeng , Zhang, Yan , Xiao, Lei and Fu, ZhiXin
Publisher
Beijing: Science China Press
Journal title
Language
English
Formats
Publication information
Publisher
Beijing: Science China Press
Subjects
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Scope and Contents
Contents
Genetically modified pigs are valuable models of human disease and donors of xenotransplanted organs.Conventional gene targeting in pig somatic cells is extremely inefficient.Zinc-finger nuclease（ZFN）technology has been shown to be a powerful tool for efficiently inducing mutations in the genome.However,ZFN-mediated targeting in pigs has rarely bee...
Alternative Titles
Full title
Generation of GGTA1 biallelic knockout pigs via zinc-finger nucleases and somatic cell nuclear transfer
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_miscellaneous_1494301636
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1494301636
Other Identifiers
ISSN
1674-7305
E-ISSN
1869-1889
DOI
10.1007/s11427-013-4601-2
