Treatment of Ethylene Glycol Poisoning with Intravenous 4-Methylpyrazole
Treatment of Ethylene Glycol Poisoning with Intravenous 4-Methylpyrazole
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Boston, MA: Massachusetts Medical Society
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Language
English
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Boston, MA: Massachusetts Medical Society
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Contents
THE toxic effects of ethylene glycol result from its metabolic conversion by alcohol dehydrogenase into glycolic acid — a process that causes metabolic acidosis. Glycolate is then metabolized to oxalate, the apparent cause of the renal toxicity of ethylene glycol. Ethanol and methanol are also metabolized by alcohol dehydrogenase, and it is the for...
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Full title
Treatment of Ethylene Glycol Poisoning with Intravenous 4-Methylpyrazole
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TN_cdi_proquest_miscellaneous_14973756
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_14973756
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ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJM198807143190206
