A phase 3, randomized, double-blind, placebo-controlled study of the safety and efficacy of the live...
A phase 3, randomized, double-blind, placebo-controlled study of the safety and efficacy of the live, oral adenovirus type 4 and type 7 vaccine, in U.S. military recruits
About this item
Full title
Author / Creator
Kuschner, Robert A , Russell, Kevin L , Abuja, Mary , Bauer, Kristen M , Faix, Dennis J , Hait, Howard , Henrick, Jennifer , Jacobs, Michael , Liss, Alan , Lynch, Julia A , Liu, Qi , Lyons, Arthur G , Malik, Mohammad , Moon, James E , Stubbs, Jeremiah , Sun, Wellington , Tang, Doug , Towle, Andrew C , Walsh, Douglas S , Wilkerson, Deborah , the Adenovirus Vaccine Efficacy Trial Consortium and Adenovirus Vaccine Efficacy Trial Consortium
Publisher
Kidlington: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Kidlington: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Highlights • An efficacy trial of a new adenovirus vaccine was performed in military recruits. • 4040 volunteers were randomized in a 3:1 ratio of vaccine to placebo. • Efficacy against ADV-4 respiratory disease was >98%. ADV-7 infection did not occur. • Vaccine was well tolerated. One placebo-recipient acquired vaccine strain of ADV-4. • The new a...
Alternative Titles
Full title
A phase 3, randomized, double-blind, placebo-controlled study of the safety and efficacy of the live, oral adenovirus type 4 and type 7 vaccine, in U.S. military recruits
Authors, Artists and Contributors
Author / Creator
Russell, Kevin L
Abuja, Mary
Bauer, Kristen M
Faix, Dennis J
Hait, Howard
Henrick, Jennifer
Jacobs, Michael
Liss, Alan
Lynch, Julia A
Liu, Qi
Lyons, Arthur G
Malik, Mohammad
Moon, James E
Stubbs, Jeremiah
Sun, Wellington
Tang, Doug
Towle, Andrew C
Walsh, Douglas S
Wilkerson, Deborah
the Adenovirus Vaccine Efficacy Trial Consortium
Adenovirus Vaccine Efficacy Trial Consortium
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1500767393
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1500767393
Other Identifiers
ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2013.04.035