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A phase 3, randomized, double-blind, placebo-controlled study of the safety and efficacy of the live...

A phase 3, randomized, double-blind, placebo-controlled study of the safety and efficacy of the live...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1500767393

A phase 3, randomized, double-blind, placebo-controlled study of the safety and efficacy of the live, oral adenovirus type 4 and type 7 vaccine, in U.S. military recruits

About this item

Full title

A phase 3, randomized, double-blind, placebo-controlled study of the safety and efficacy of the live, oral adenovirus type 4 and type 7 vaccine, in U.S. military recruits

Publisher

Kidlington: Elsevier Ltd

Journal title

Vaccine, 2013-06, Vol.31 (28), p.2963-2971

Language

English

Formats

Publication information

Publisher

Kidlington: Elsevier Ltd

More information

Scope and Contents

Contents

Highlights • An efficacy trial of a new adenovirus vaccine was performed in military recruits. • 4040 volunteers were randomized in a 3:1 ratio of vaccine to placebo. • Efficacy against ADV-4 respiratory disease was >98%. ADV-7 infection did not occur. • Vaccine was well tolerated. One placebo-recipient acquired vaccine strain of ADV-4. • The new a...

Alternative Titles

Full title

A phase 3, randomized, double-blind, placebo-controlled study of the safety and efficacy of the live, oral adenovirus type 4 and type 7 vaccine, in U.S. military recruits

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1500767393

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1500767393

Other Identifiers

ISSN

0264-410X

E-ISSN

1873-2518

DOI

10.1016/j.vaccine.2013.04.035

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