Stem cell CD44v isoforms promote intestinal cancer formation in Apc(min) mice downstream of Wnt sign...
Stem cell CD44v isoforms promote intestinal cancer formation in Apc(min) mice downstream of Wnt signaling
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Author / Creator
Zeilstra, J , Joosten, S P J , van Andel, H , Tolg, C , Berns, A , Snoek, M , van de Wetering, M , Spaargaren, M , Clevers, H and Pals, S T
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
A gene signature specific for intestinal stem cells (ISCs) has recently been shown to predict relapse in colorectal cancer (CRC) but the tumorigenic role of individual signature genes remains poorly defined. A prominent ISC-signature gene is the cancer stem cell marker CD44, which encodes various splice variants comprising a diverse repertoire of a...
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Full title
Stem cell CD44v isoforms promote intestinal cancer formation in Apc(min) mice downstream of Wnt signaling
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Record Identifier
TN_cdi_proquest_miscellaneous_1500790704
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1500790704
Other Identifiers
ISSN
0950-9232,1476-5594
E-ISSN
1476-5594
DOI
10.1038/onc.2012.611
