UV-Photoconversion of Ethosuximide from a Longevity-Promoting Compound to a Potent Toxin: e82543
UV-Photoconversion of Ethosuximide from a Longevity-Promoting Compound to a Potent Toxin: e82543
About this item
Full title
UV-Photoconversion of Ethosuximide from a Longevity-Promoting Compound to a Potent Toxin: e82543
Author / Creator
Journal title
PloS one, 2013-12, Vol.8 (12)
Language
English
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Scope and Contents
Contents
The anticonvulsant ethosuximide has been previously shown to increase life span and promote healthspan in the nematode Caenorhabditis elegans at millimolar concentrations. Here we report that following exposure to ultraviolet irradiation at 254 nm, ethosuximide is converted into a compound that displays toxicity toward C. elegans. This effect is sp...
Alternative Titles
Full title
UV-Photoconversion of Ethosuximide from a Longevity-Promoting Compound to a Potent Toxin: e82543
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Record Identifier
TN_cdi_proquest_miscellaneous_1500798680
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1500798680
Other Identifiers
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0082543
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