Early Onset of Diabetes in the Proband Is the Major Determinant of Risk in HLA DR3-DQ2/DR4-DQ8 Sibli...
Early Onset of Diabetes in the Proband Is the Major Determinant of Risk in HLA DR3-DQ2/DR4-DQ8 Siblings
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Author / Creator
Publisher
Alexandria, VA: American Diabetes Association
Journal title
Language
English
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Publication information
Publisher
Alexandria, VA: American Diabetes Association
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Scope and Contents
Contents
Islet autoimmunity is initiated in infancy, and primary prevention trials require children at high genetic risk to be identified before autoantibodies appear. To inform screening strategies, we evaluated risks of autoimmunity and diabetes associated with HLA DR3-DQ2/DR4-DQ8 in U.K. families. Extended HLA haplotypes were determined in 2,134 siblings...
Alternative Titles
Full title
Early Onset of Diabetes in the Proband Is the Major Determinant of Risk in HLA DR3-DQ2/DR4-DQ8 Siblings
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Record Identifier
TN_cdi_proquest_miscellaneous_1501370353
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1501370353
Other Identifiers
ISSN
0012-1797
E-ISSN
1939-327X
DOI
10.2337/db13-0994
