Growth Factors Engineered for Super-Affinity to the Extracellular Matrix Enhance Tissue Healing
Growth Factors Engineered for Super-Affinity to the Extracellular Matrix Enhance Tissue Healing
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Publisher
United States: American Association for the Advancement of Science
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Language
English
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Publisher
United States: American Association for the Advancement of Science
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Contents
Growth factors (GFs) are critical in tissue repair, but their translation to clinical use has been modest. Physiologically, GF interactions with extracellular matrix (ECM) components facilitate localized and spatially regulated signaling; therefore, we reasoned that the lack of ECM binding in their clinically used forms could underlie the limited t...
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Growth Factors Engineered for Super-Affinity to the Extracellular Matrix Enhance Tissue Healing
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TN_cdi_proquest_miscellaneous_1501371277
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1501371277
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1247663