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Growth Factors Engineered for Super-Affinity to the Extracellular Matrix Enhance Tissue Healing

Growth Factors Engineered for Super-Affinity to the Extracellular Matrix Enhance Tissue Healing

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1501371277

Growth Factors Engineered for Super-Affinity to the Extracellular Matrix Enhance Tissue Healing

About this item

Full title

Growth Factors Engineered for Super-Affinity to the Extracellular Matrix Enhance Tissue Healing

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2014-02, Vol.343 (6173), p.885-888

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Growth factors (GFs) are critical in tissue repair, but their translation to clinical use has been modest. Physiologically, GF interactions with extracellular matrix (ECM) components facilitate localized and spatially regulated signaling; therefore, we reasoned that the lack of ECM binding in their clinically used forms could underlie the limited t...

Alternative Titles

Full title

Growth Factors Engineered for Super-Affinity to the Extracellular Matrix Enhance Tissue Healing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1501371277

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1501371277

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1247663

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