Tumor Protein p53 (TP53) Testing and Li-Fraumeni Syndrome: Current Status of Clinical Applications a...
Tumor Protein p53 (TP53) Testing and Li-Fraumeni Syndrome: Current Status of Clinical Applications and Future Directions
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Publisher
Cham: Springer International Publishing AG
Journal title
Language
English
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Publisher
Cham: Springer International Publishing AG
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Scope and Contents
Contents
Prevalent as an acquired abnormality in cancer, the role of tumor protein p53 (
TP53
) as a germline mutation continues to evolve. The clinical impact of a germline
TP53
mutation is often dramatic and affects the full life course, with a propensity to develop rare tumors in childhood and multiple common cancers of unexpectedly early ons...
Alternative Titles
Full title
Tumor Protein p53 (TP53) Testing and Li-Fraumeni Syndrome: Current Status of Clinical Applications and Future Directions
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Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_1505334815
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1505334815
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ISSN
1177-1062
E-ISSN
1179-2000
DOI
10.1007/s40291-013-0020-0