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Tumor Protein p53 (TP53) Testing and Li-Fraumeni Syndrome: Current Status of Clinical Applications a...

Tumor Protein p53 (TP53) Testing and Li-Fraumeni Syndrome: Current Status of Clinical Applications a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1505334815

Tumor Protein p53 (TP53) Testing and Li-Fraumeni Syndrome: Current Status of Clinical Applications and Future Directions

About this item

Full title

Tumor Protein p53 (TP53) Testing and Li-Fraumeni Syndrome: Current Status of Clinical Applications and Future Directions

Publisher

Cham: Springer International Publishing AG

Journal title

Molecular diagnosis & therapy, 2013-02, Vol.17 (1), p.31-47

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing AG

More information

Scope and Contents

Contents

Prevalent as an acquired abnormality in cancer, the role of tumor protein p53 (
TP53
) as a germline mutation continues to evolve. The clinical impact of a germline
TP53
mutation is often dramatic and affects the full life course, with a propensity to develop rare tumors in childhood and multiple common cancers of unexpectedly early ons...

Alternative Titles

Full title

Tumor Protein p53 (TP53) Testing and Li-Fraumeni Syndrome: Current Status of Clinical Applications and Future Directions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1505334815

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1505334815

Other Identifiers

ISSN

1177-1062

E-ISSN

1179-2000

DOI

10.1007/s40291-013-0020-0

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