Decreased Mutation Frequencies among Immunoglobulin G Variable Region Genes during Viremic HIV-1 Inf...
Decreased Mutation Frequencies among Immunoglobulin G Variable Region Genes during Viremic HIV-1 Infection: e81913
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Full title
Decreased Mutation Frequencies among Immunoglobulin G Variable Region Genes during Viremic HIV-1 Infection: e81913
Author / Creator
Journal title
PloS one, 2014-01, Vol.9 (1)
Language
English
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Contents
Background/objective HIV-1 infection is complicated by high rates of opportunistic infections against which specific antibodies contribute to immune defense. Antibody function depends on somatic hypermutation (SHM) of variable regions of immunoglobulin heavy chain genes (VH-D-J). We characterized the frequency of SHM in expressed IgG mRNA immunoglo...
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Full title
Decreased Mutation Frequencies among Immunoglobulin G Variable Region Genes during Viremic HIV-1 Infection: e81913
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Record Identifier
TN_cdi_proquest_miscellaneous_1505337137
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1505337137
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E-ISSN
1932-6203
DOI
10.1371/journal.pone.0081913
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