Blinded versus Unblinded Covariate Selection in Confirmatory Survival Trials
Blinded versus Unblinded Covariate Selection in Confirmatory Survival Trials
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Author / Creator
Publisher
England: Taylor & Francis Group
Journal title
Language
English
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Publication information
Publisher
England: Taylor & Francis Group
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Scope and Contents
Contents
Adjustment for covariates and specification of the correct covariate set are important issues in the analysis of clinical trials. Edwards (
1999
) proposes a model selection approach where the model is chosen on the final data set, which remains blinded for treatment group allocation. We investigate this method for time-to-event endpoints and...
Alternative Titles
Full title
Blinded versus Unblinded Covariate Selection in Confirmatory Survival Trials
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Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_1520991239
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1520991239
Other Identifiers
ISSN
1054-3406
E-ISSN
1520-5711
DOI
10.1080/10543406.2013.860158