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Blinded versus Unblinded Covariate Selection in Confirmatory Survival Trials

Blinded versus Unblinded Covariate Selection in Confirmatory Survival Trials

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1520991239

Blinded versus Unblinded Covariate Selection in Confirmatory Survival Trials

About this item

Full title

Blinded versus Unblinded Covariate Selection in Confirmatory Survival Trials

Publisher

England: Taylor & Francis Group

Journal title

Journal of biopharmaceutical statistics, 2014-03, Vol.24 (2), p.398-414

Language

English

Formats

Publication information

Publisher

England: Taylor & Francis Group

More information

Scope and Contents

Contents

Adjustment for covariates and specification of the correct covariate set are important issues in the analysis of clinical trials. Edwards (
1999
) proposes a model selection approach where the model is chosen on the final data set, which remains blinded for treatment group allocation. We investigate this method for time-to-event endpoints and...

Alternative Titles

Full title

Blinded versus Unblinded Covariate Selection in Confirmatory Survival Trials

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1520991239

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1520991239

Other Identifiers

ISSN

1054-3406

E-ISSN

1520-5711

DOI

10.1080/10543406.2013.860158

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