Hippocampal Neurogenesis Regulates Forgetting During Adulthood and Infancy
Hippocampal Neurogenesis Regulates Forgetting During Adulthood and Infancy
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Author / Creator
Akers, Katherine G. , Martinez-Canabal, Alonso , Restivo, Leonardo , Yiu, Adelaide P. , De Cristofaro, Antonietta , Hsiang, Hwa-Lin (Liz) , Wheeler, Anne L. , Guskjolen, Axel , Niibori, Yosuke , Shoji, Hirotaka , Ohira, Koji , Richards, Blake A. , Miyakawa, Tsuyoshi , Josselyn, Sheena A. and Frankland, Paul W.
Publisher
United States: American Association for the Advancement of Science
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Language
English
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Publisher
United States: American Association for the Advancement of Science
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Contents
Throughout life, new neurons are continuously added to the dentate gyrus. As this continuous addition remodels hippocampal circuits, computational models predict that neurogenesis leads to degradation or forgetting of established memories. Consistent with this, increasing neurogenesis after the formation of a memory was sufficient to induce forgett...
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Full title
Hippocampal Neurogenesis Regulates Forgetting During Adulthood and Infancy
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TN_cdi_proquest_miscellaneous_1523406003
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1523406003
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1248903