An intragenic ERG deletion is a marker of an oncogenic subtype of B-cell precursor acute lymphoblast...
An intragenic ERG deletion is a marker of an oncogenic subtype of B-cell precursor acute lymphoblastic leukemia with a favorable outcome despite frequent IKZF1 deletions
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Author / Creator
Clappier, E , Auclerc, M-F , Rapion, J , Bakkus, M , Caye, A , Khemiri, A , Giroux, C , Hernandez, L , Kabongo, E , Savola, S , Leblanc, T , Yakouben, K , Plat, G , Costa, V , Ferster, A , Girard, S , Fenneteau, O , Cayuela, J-M , Sigaux, F , Dastugue, N , Suciu, S , Benoit, Y , Bertrand, Y , Soulier, J and Cavé, H
Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
Oncogenic subtypes in childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL) are used for risk stratification. However, a significant number of BCP-ALL patients are still genetically unassigned. Using array-comparative genomic hybridization in a selected BCP-ALL cohort, we characterized a recurrent V(D)J-mediated intragenic deletion of t...
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Full title
An intragenic ERG deletion is a marker of an oncogenic subtype of B-cell precursor acute lymphoblastic leukemia with a favorable outcome despite frequent IKZF1 deletions
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Record Identifier
TN_cdi_proquest_miscellaneous_1524395512
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1524395512
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ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/leu.2013.277
