Effects of low-fat and high-fat meals on steady-state pharmacokinetics of lapatinib in patients with...
Effects of low-fat and high-fat meals on steady-state pharmacokinetics of lapatinib in patients with advanced solid tumours
About this item
Full title
Author / Creator
Publisher
New York: Springer US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Springer US
Subjects
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Scope and Contents
Contents
Summary
Aim
To quantify the effect of food on the systemic exposure of lapatinib at steady state when administered 1 h before and after meals, and to observe the safety and tolerability of lapatinib under these conditions in patients with advanced solid tumours.
Methods
This was a three-treatment, randomised, three-sequence cross-over s...
Alternative Titles
Full title
Effects of low-fat and high-fat meals on steady-state pharmacokinetics of lapatinib in patients with advanced solid tumours
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1532950528
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1532950528
Other Identifiers
ISSN
0167-6997,1573-0646
E-ISSN
1573-0646
DOI
10.1007/s10637-013-0055-4
