Pivoting between Calmodulin Lobes Triggered by Calcium in the Kv7.2/Calmodulin Complex: e86711
Pivoting between Calmodulin Lobes Triggered by Calcium in the Kv7.2/Calmodulin Complex: e86711
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Full title
Pivoting between Calmodulin Lobes Triggered by Calcium in the Kv7.2/Calmodulin Complex: e86711
Author / Creator
Journal title
PloS one, 2014-01, Vol.9 (1)
Language
English
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Scope and Contents
Contents
Kv7.2 (KCNQ2) is the principal molecular component of the slow voltage gated M-channel, which strongly influences neuronal excitability. Calmodulin (CaM) binds to two intracellular C-terminal segments of Kv7.2 channels, helices A and B, and it is required for exit from the endoplasmic reticulum. However, the molecular mechanisms by which CaM contro...
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Full title
Pivoting between Calmodulin Lobes Triggered by Calcium in the Kv7.2/Calmodulin Complex: e86711
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Record Identifier
TN_cdi_proquest_miscellaneous_1534827747
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1534827747
Other Identifiers
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0086711
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