Role of Ras, ERK, and Akt in glucocorticoid-induced differentiation of embryonic rat somatotropes in...
Role of Ras, ERK, and Akt in glucocorticoid-induced differentiation of embryonic rat somatotropes in vitro
About this item
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Author / Creator
Lv, Wen Ming , Zhao, Yan , Yang, Guang , Dong, Shi Yun , Zhang, Guang Hui , Zhang, Yu , Li, Guo Zhong and Cheng, Yu
Publisher
New York: Springer US
Journal title
Language
English
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Publication information
Publisher
New York: Springer US
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Contents
This study investigated the roles of Ras, ERK, and Akt in the glucocorticoid-induced differentiation of growth hormone-producing pituitary cells in vitro. Pituicytes isolated from day-18 rat embryos were cultured with 50 mM dexamethasone in addition to specific inhibitors of Ras (manumycin; 0.5, 5, 50 nM), ERK (U0126, 10 μM), or Akt (LY294002, 25 μ...
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Full title
Role of Ras, ERK, and Akt in glucocorticoid-induced differentiation of embryonic rat somatotropes in vitro
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Record Identifier
TN_cdi_proquest_miscellaneous_1534839295
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1534839295
Other Identifiers
ISSN
0300-8177
E-ISSN
1573-4919
DOI
10.1007/s11010-014-1988-4
