Log in to save to my catalogue

Characterization of a Novel Single-Chain Bispecific Antibody for Retargeting of T Cells to Tumor Cel...

Characterization of a Novel Single-Chain Bispecific Antibody for Retargeting of T Cells to Tumor Cel...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1534843716

Characterization of a Novel Single-Chain Bispecific Antibody for Retargeting of T Cells to Tumor Cells via the TCR Co-Receptor CD8: e95517

About this item

Full title

Characterization of a Novel Single-Chain Bispecific Antibody for Retargeting of T Cells to Tumor Cells via the TCR Co-Receptor CD8: e95517

Journal title

PloS one, 2014-04, Vol.9 (4)

Language

English

Formats

More information

Scope and Contents

Contents

There is currently growing interest in retargeting of effector T cells to tumor cells via bispecific antibodies (bsAbs). Usually, bsAbs are directed on the one hand to the CD3 complex of T cells and on the other hand to a molecule expressed on the surface of the target cell. A bsAb-mediated cross-linkage via CD3 leads to an activation of CD8+ T cel...

Alternative Titles

Full title

Characterization of a Novel Single-Chain Bispecific Antibody for Retargeting of T Cells to Tumor Cells via the TCR Co-Receptor CD8: e95517

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1534843716

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1534843716

Other Identifiers

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0095517

How to access this item