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Methylglyoxal impairs endothelial insulin sensitivity both in vitro and in vivo

Methylglyoxal impairs endothelial insulin sensitivity both in vitro and in vivo

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1535212435

Methylglyoxal impairs endothelial insulin sensitivity both in vitro and in vivo

About this item

Full title

Methylglyoxal impairs endothelial insulin sensitivity both in vitro and in vivo

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Diabetologia, 2014-07, Vol.57 (7), p.1485-1494

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Aims/hypothesis
Insulin exerts a direct action on vascular cells, thereby affecting the outcome and progression of diabetic vascular complications. However, the mechanism through which insulin signalling is impaired in the endothelium of diabetic individuals remains unclear. In this work, we have evaluated the role of the AGE precursor methylgly...

Alternative Titles

Full title

Methylglyoxal impairs endothelial insulin sensitivity both in vitro and in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1535212435

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1535212435

Other Identifiers

ISSN

0012-186X

E-ISSN

1432-0428

DOI

10.1007/s00125-014-3243-7

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