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Protection from liver fibrosis by a peroxisome proliferator-activated receptor δ agonist

Protection from liver fibrosis by a peroxisome proliferator-activated receptor δ agonist

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1539445654

Protection from liver fibrosis by a peroxisome proliferator-activated receptor δ agonist

About this item

Full title

Protection from liver fibrosis by a peroxisome proliferator-activated receptor δ agonist

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (21), p.E1369-E1376

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Peroxisome proliferator-activated receptor delta (PPARδ), a member of the nuclear receptor family, is emerging as a key metabolic regulator with pleiotropic actions on various tissues including fat, skeletal muscle, and liver. Here we show that the PPARδ agonist KD3010, but not the well-validated GW501516, dramatically ameliorates liver injury indu...

Alternative Titles

Full title

Protection from liver fibrosis by a peroxisome proliferator-activated receptor δ agonist

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1539445654

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1539445654

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1202464109

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